Analysis of Protein-RNA Interactions at Atomic Level∗

Many studies of protein-RNA complexes focus on protein instead of RNA or both, and often ignore water-mediated protein-RNA complexes despite their abundant existence. The primary focus of our study is to find interaction propensities not only for proteins but also for RNAs. This paper presents the analysis of 952 hydrogen bonds in the most representative set of protein-RNA complexes, including both direct hydrogen bonds and water-mediated hydrogen bonds.